Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
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*Please contact your Endress+Hauser sales partner for any further questions.
Specs at a glance
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Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish
Adhesive: USP Class VI and ISO 10993 compatible -
Sterilization method
CIP/SIP
Field of application
The Raman flow cell meets the speed demands of downstream by optimizing Raman collection for low-turbidity, low volume samples. Ideally suited for development-scale flow rates, the Raman flow cell allows real-time monitoring, rapid process optimization, and process control for chromatography and other downstream unit operations.
Downstream: aggregation, protein crystallization, formula stability, product CQA, protein concentration, buffer excipients
Benefits
The Raman flow bench houses a Raman flow cell and easily connects to an Rxn-10 probe paired with a Raman Rxn embedded analyzer, and ensures transferability when used with the Raman flow assembly calibration and verification kit
Provides continuous, real-time measurements with high sensitivity for development-scale flow rates
Achieves lower limits of detection through enhancement of the Raman signal
Brings Raman-based process insights and control to downstream bioprocessing unit operations
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
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Success stories
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24 documents
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Technical Information (TI)
Raman flow assembly calibration and verification kit Technical Information
System design and specifications for the Raman flow assembly calibration
and verification kitLanguage:
English
Version:
29/06/2023
File size:
430.9 KB
File name:
TI01720CEN_0123 Raman flow assembly calibration and verification kit.pdf
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Technical Information (TI)
Raman flow assembly Technical Information
System design and specifications for the Raman flow assembly
(KRFB, KRFC)Language:
English
Version:
30/06/2023
File size:
329.5 KB
File name:
TI01721CEN_0123.pdf
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Operating Instruction (BA)
Raman flow assembly calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
Raman flow assembly calibration and verification kitLanguage:
English
Version:
29/06/2023
File size:
1006.6 KB
File name:
BA02295CEN_0123 Raman flow assembly calibration and verification kit.pdf
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Operating Instruction (BA)
Raman flow assembly Operating Instructions
Commissioning, operation, and maintenance details for the
Raman flow assembly (KRFB, KRFC)Language:
English
Version:
30/06/2023
File size:
951.5 KB
File name:
BA02296CEN_0123.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.7 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Raman flow assembly - Precise composition measurement of high-speed, low-volume samples in downstream bioprocessing
An overview of the Raman flow assembly (flow bench and flow cell)
used with the Rxn-10 probe in conjunction with a Raman Rxn2
analyzer and a Raman flow assembly calibration and verification kit
for downstream bioprocessing (powered by Kaiser Raman technology).Language:
English
Version:
31/05/2023
File size:
837 KB
File name:
PU01517CEN_0123.pdf
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PU (Publication)
Raman calibration and verification kits - Everything needed to calibrate and verify your Raman analyzer system for lab-to-process scalability
An overview of the Raman calibration and verification kits for
the bio multi optic / single use optic and the Raman flow assembly
(includes the flow bench and flow cell). These kits are to be used in
conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer
for upstream and downstream bioprocessing (powered by Kaiser
Raman technology).Language:
English
Version:
13/12/2023
File size:
2.1 MB
File name:
PU01518CEN_0223.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
English
Version:
27/06/2024
File size:
753.7 KB
File name:
PU01584CEN_0124.pdf
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